According to Betty Kamen, Ph.D., and
author of the book, "New Facts About Fiber" (Health Builder, Disease
Fighter, Vital Nutrient), she states to look for and add these fibers when
supplementing your diet: Acerola fiber, apple fiber, barley fiber, beet
fiber, carrot fiber, chickpea fiber, fig fiber, flax seed fiber, guar gum,
gum arabic, gums (other), locust bean gum, oat bran, pectin, prune powder,
psyllium husks, rice bran. These fibers contain both soluble and insoluble
fibers!
Fibresonic...what an excellent choice!
Check out the 19 different "real food" fiber sources
found in "Fibresonic!" There are specific health benefits associated with
each and every one of them and the taste plus the results you get will
convince you it's the best on the market! The other ingredients and
nutrients have a synergetic effect with the fiber to impact your cells and
your life! Fibresonic Ingredients: Fructose, Sorbitol, Vegetable Oil
Powder Preparation (Non Hydrogenated Sun Flower Oil, Corn Syrup
Solids, Sodium Caseinate, Mono and Diglycerides, Dipotassium
Phosphate, Sodium Silicoaluminate and lecithin). Yogurt Powder,
Soy Fiber, Gum Arabic, Cellulose Gel/Gum, Cellulose Fiber, Pea
Fiber, Corn Bran, Guar Gum, Calcium Caseinate, Locust Bean Gum,
Wheat Bran, Sugar Beet Fiber, Natural Vanilla Flavor with other
Natural Flavors, Rice Bran, Natural Almond Flavor with other
Natural Flavors (with Peanut Oil), Beta Carotene, Lecithin,
Xanthan Gum, Citrus Pectin, Oat Fiber, Prune Fiber (low Moisture
Prune and Calcium Stearate), Barley Bran, Vitamin C (Ascorbic
Acid), Dicalcium Phosphate, Vitamin E (dl-Alpha-Tocopheryl
Acetate), Pear Fiber, Fig Fiber, Apple Fiber, Vitamin C Palmitate
(Ascorbyl Palmitate), Vitamin A (Vitamin A Palmitate), Niacin (Niacinamide),
Zinc Oxide, Iron Electrolytic, Copper Gluconate, Pantothenic Acid
(d-Calcium Pantothenate), Vitamin D-3 (Cholecalciferol), Vitamin
B-6 (Pyridoxine Hydrochloride), Vitamin B-2 (Riboflavin), Chromium
Chelate, Vitamin B-1 (Thiamine Mononitrate), Folic Acid, Biotin,
Copper Chelate, Calcium Chelate, Manganese Chelate, Zinc Chelate,
Magnesium Chelate, Iron Chelate, Lactobacillus acidophilus,
Potassium Iodide and Vitamin B-12 (Cyanocobalamin).
Facts about Fiber
Apple fiber: Fruit fibers are popular because of their
pectin content. Pectin is found to interact specifically with
LDL-cholesterol, suggesting a biochemical basis by which it causes lower
cholesterol levels. The higher your LDL-cholesterol level, the higher the
risk for arteriosclerosis. Pectin is available from a wide range of
fruits. (Commercial pectins, however, are produced almost entirely from
citrus peel.) Generally, pectin slows gastric-emptying time (the first
phase of transit movement, when it is preferable for the food mass to move
slowly.) It improves glucose tolerance, and may act through a mechanism
similar to that of bile-acid binding in lowering plasma-cholesterol
levels. Pectins are especially powerful in protecting against the toxic
effects of some of the chemicals we consume with our food. Pectin reduces
cholesterol concentrations an average of 13 percent. It increases fecal
fat excretion by 44 percent and fecal bile acid excretion by 33 percent.
Barley bran/barley fiber: Cereal grains and palm oil
contain Vitamin E (tocopherols) and tocotrienols. You may already be
familiar with tocopherol as a lipid (fat) antioxidant, but the
tocotrienols and their incredible functions have not yet received much
press. Dr. Lester Packer, Ph.D., of the Department of Molecular and Cell
Biology, University of California, Berkeley, says tocotrienols are many
times superior to tocopherols in their role as antioxidants. When
administered to test animals, these heavy-duty antioxidants increase
lifespan, prevent platelet aggregation, and reduce cholesterol. Platelet
adhesiveness, or aggregation refers to the clumping together of plate-like
structures that appear in your blood which, when bunched up, restrict
blood flow and contribute to heart disease. Researchers at the University
of Wisconsin have identified tocotrienols in the oil of barley bran. It
has been known for some time that tocotrienols are found in the layers of
cereal seeds, and their isolation from barley bran is truly exciting.
Barley bran also lowers cholesterol concentration in both serum and bile
in test animals with gallstones. And it dissolves their previously formed
gallstones.
Guar gum: Guar gum is derived from the outer part of
Cyanopsis tetragonolobus, a leguminous vegetable that grows in India. Guar
prevents blood sugar from rising excessively after ingesting sweetened
foods, so it is used adjunct in treating diabetics. Guar also flattens
glucose and insulin responses in normal people, and even patients who have
gastric surgery. Guar, as with psyllium, accumulates water and forms gels
in your intestinal tract, apparently delaying the absorption of the simple
carbohydrates like sugar. Guar moderates sugar absorption better than any
other fiber. Clinical trials indicate that guar gum may reduce cholesterol
by 10 to 15 percent. The mechanism of action is thought to be similar to
that of bile-acid binding and its capacity to reduce LDL.
Gum arabic: When certain plants are injured or exposed
to adverse conditions, they exude a gummy material which dries in the form
of lumps or ribbons. After collection and purification, the gum has many
applications. In fact it has been put to use for more than four thousand
years. Gum arabic is such a gum. Today, it is used in candy glazes, cough
drops, lozenges, and as an addition to fiber supplements. A large
percentage of ingested gum arabic may be assimilated and used for energy.
Lecithin: Lecithin is needed by every cell in the
human body. Cell membranes, that regulate which nutrients may leave or
enter the cell, are largely composed of lecithin. Without lecithin the
cell membranes would harden. Its structure protects the cells from damage
by oxidation. The protective sheaths surrounding the brain are composed of
lecithin, and the muscles and nerve cells also contain this essential
fatty substance. It is largely composed of the B vitamin choline, and
contains linoleic acid and inositol. Although lecithin is a fatty
substance, it acts as an emulsifying agent. It is especially important
that the elderly obtain this nutrient because it helps prevent
arteriosclerosis, protects against cardiovascular disease, brain function,
and aids in the absorption of thiamine by the liver and vitamin A by the
intestine. Lecithin is also known to promote energy and is needed to help
repair the damage to the liver caused by alcoholism.
Locust bean gum: Locust bean gum is obtained from the
seeds of the carob tree, an evergreen species indigenous to semi-arid
areas of Spain, Italy, Greece, Cyprus, and Israel. It acts as a thickener
and water-control agent in various foods. It is only slightly degraded
during its trip through your gastrointestinal tract. Breakdown occurs by
the micro-flora at the end of the line. This fiber, like so many others,
causes a decrease in total cholesterol due primarily to a decline in the
LDL-cholesterol fraction.
Oat fiber: Oat fiber may be accompanied by a greater
reduction in cholesterol than oat bran. The cholesterol-lowering effect of
oat fiber is associated with its soluble fiber content. Oat fiber, which
is extracted from oat bran, is more concentrated. WARNING: Some companies
sell a products called oat fiber, which is made from oat hulls. These are
high in fiber, but are insoluble, and will not lower elevated cholesterol.
These products are relatively cheap and potentially deceptive.
Pea fiber: Fresh green peas became popular after a
craze for them flourished at the court of King Louis XIV, when the passion
for peas was described as "a fashion and a madness." Until then, they were
eaten dried. Today, pea fiber is also a new kid on the fiber block. Pea
fiber has a cholesterol lowering effect. Peas contain Lysine, an essential
amino acid often in short supply for vegetarians. Pea fiber decreases
blood glucose curves significantly, and is helpful for those who eat
sweets as well as for diabetics because of its sugar-controlling effect.
Egyptian research conducted years ago demonstrated that injecting pea
extracts into the veins of dogs caused a temporary decrease in blood
pressure.
Rice bran: It could be said that rice and humans have
established a symbiotic relationship throughout much of the world.
Oryzanol, a substance found in the oil of rice bran, has unique
implications for human nutrition. The biological name for rice is Oryza
sativa, thus the name oryzanol. Even small doses of oryzanol enable
certain cholesterol-controlling enzymes in your liver to function more
effectively. The protective properties of oryzanol go beyond that of
simply lowering cholesterol. It also reduces deposits of various other
unwanted collections in your arteries. The study of oryzanol makes one
wonder how a single substance can contain such an efficient mix of
synergistic ingredients with such a wide range of protective
contributions. Rice has long since been the world's most popular staple
food--culled from millennia of observant trial and error. The dietary
habits of survivors across the meshes of time have always been regarded as
noteworthy and should continue to command our attention! Research
investigating its effects on colonic function show that it increases fecal
mass and stool frequency. In one significant study, ten patients with too
much urinary calcium excretion were given rice bran for sixty days. The
problem was reduced in all patients by an average of 40 percent. Death
associated with gallstones occurs when test animals are fed diets without
fiber, but its incidence is eliminated by feeding the animals the same
diet with rice flour plus fiber! (Matol does no animal testing whatsoever
with its products!)
Sugar beet fiber: Beet fiber has more soluble fiber
than oat bran or rice bran, and very much more insoluble fiber than
either. It helps to normalize systolic blood pressure, decreases total
cholesterol while increasing HDL-cholesterol, thereby lowering the LDL-HDL
ratio, curbs triglyceride levels, improves glucose tolerance, enhances
iron and zinc absorption, important implications for mineral nutrition.
One of the problems with beets is that they require a lot of cooking which
depletes their valuable Vitamin B6 content. Processed or canned beets are
subjected to even higher temperatures. Eating beets raw goes back to the
measures that out of kilter with our lifestyle, so finding this fiber in a
supplement that is not over processed is an asset!
Wheat bran: As already noted, different cereal brans
have distinct chemistries and water-holding capacities. Bran, for example,
is different in hard, soft, or Durham wheat. The same applies to varieties
of fruits and vegetables. Bran in general reduces the number of tumors
induced by chemical carcinogens. Wheat bran may be effective in retarding
colon cancer. Wheat bran is shown to lower blood glucose and to increase
the intestinal absorption of zinc. Although wheat bran does not have
important cholesterol-lowering effects, it drops cholesterol
concentrations in diabetic patients by 30 percent when administered with
guar gum. No doubt there are many other synergistic effects at work that
are still unknown--one more reason for variety in fiber and food
selections. Like so many other natural substances, wheat bran is also an
adaptogenic, operating only in the presence of need. In those with normal
bile function, the addition of wheat bran has no effect on bile
cholesterol.
Matol also included yogurt powder, soy fiber, cellulose
gum-gel, cellulose fiber, corn bran, tofu fiber, xanthan gum, prune fiber,
pear fiber, and fig fiber, along with other nutrient factors to give Fibresonic the "Cadillac Effect" in the needed fiber you have been missing
in your life! All of these added fibers play a role in the combination of
this high quality product. It was designed to enhance your health beyond
any ordinary fiber supplementation found on the market today!
Lecithin: Lecithin is needed by every cell in the
human body. Cell membranes, that regulate which nutrients may leave or
enter the cell, are largely composed of lecithin. Without lecithin the
cell membranes would harden. Its structure protects the cells from damage
by oxidation. The protective sheaths surrounding the brain are composed of
lecithin, and the muscles and nerve cells also contain this essential
fatty substance. It is largely composed of the B vitamin choline, and
contains linoleic acid and inositol. Although lecithin is a fatty
substance, it acts as an emulsifying agent. It is especially important
that the elderly obtain this nutrient because it helps prevent
arteriosclerosis, protects against cardiovascular disease, brain function,
and aids in the absorption of thiamine by the liver and vitamin A by the
intestine. Lecithin is also known to promote energy and is needed to help
repair the damage to the liver caused by alcoholism.
Beta-Carotene (Vitamin A): This nutrient prevents
night blindness and other eye problems as well as some skin disorders such
as acne. It enhances immunity, may heal gastrointestinal ulcers, protects
against pollution and cancer formation, and is needed for epithelial
tissue maintenance and repair. It is important in the formation of bones
and teeth, aids in fat storage, and protects against colds, influenza, and
infections. Vitamin A acts as an antioxidant, which helps protect the
cells against cancer and other diseases. This important vitamin also slows
the aging process. Protein cannot be assimilated without this supplement.
When food containing beta-carotene is consumed, it is converted to vitamin
A in the liver. Beta-carotene aids in cancer prevention, according to
recent reports.
Vitamin B1 (thiamine): Thiamine enhances circulation
and assists in the production of hydrochloric acid, blood formation, and
carbohydrate metabolism. Thiamine effects energy, growth disorders, and
learning capacity, and is needed for normal muscle tone of the intestines,
stomach, and heart.
Vitamin B2 (riboflavin): Riboflavin is necessary for
red blood cell formation, antibody production, cell respiration, and
growth. It alleviates eye fatigue and is important in the prevention and
treatment of cataracts. It aids in the metabolism of carbohydrates, fats,
and proteins. When used with Vitamin A, it maintains and improves the
mucous membranes in the digestive tract. Riboflavin also facilitates
oxygen use by the body tissues (skin, nails, hair), eliminates dandruff,
and helps the uptake of iron and vitamin B6. Vitamin B2 is important
during pregnancy because a lack of this vitamin may damage the fetus even
though the mother may be unaware of a deficiency. B2 is needed for the
metabolism of tryptophan, which is converted to niacin in the body. Carpal
tunnel syndrome may benefit from a treatment program that includes
riboflavin and B6. Deficiency symptoms include cracks and sores at the
corner of the mouth.
Vitamin B3 (niacin, niacinamide): This nutrient is
needed for proper circulation and healthy skin. It aids in the functioning
of the nervous system, in the metabolism of carbohydrates, fats, and
proteins, and in the production of hydrochloric acid for the digestive
system. Niacin lowers cholesterol and improves circulation. It is also
effective in the treatment of schizophrenia and other mental illness.
Vitamin B5 (pantothenic acid): Known as the
"anti-stress" vitamin, pantothenic acid plays a role in the production of
the adrenal hormones and formulation of antibodies, aids in vitamin
utilization, and helps to convert fats, carbohydrates, and proteins into
energy. This vitamin is needed to produce vital steroids and cortisone in
the adrenal gland, and is an essential element of coenzyme A. It is
required by all cells in the body and is concentrated in the organs. It is
also needed for normal functioning of the gastrointestinal tract and may
be helpful in treating depression and anxiety.
Vitamin B6 (pyridoxine): Pridoxine is involved in more
body functions than any other single nutrient. It affects both physical
and mental health. It is beneficial if you suffer from water retention. It
is necessary in the production of hydrochloric acid and the absorption of
fats and protein. Pyridoxine also aids in maintaining sodium and potassium
balance, and promotes red blood cell formation. It is required by the
nervous system, and is needed for normal brain function and for the
synthesis of RNA and DNA (nucleic acids), which contain the genetic
instructions for the reproduction of all cells and for normal cell growth.
It activates many enzymes and aids in B12 absorption, immune system
function, and antibody production. Vitamin B6 has a role in cancer
immunity and arteriosclerosis. It inhibits the formation of a toxic
chemical called homocysteine, which attacks the heart muscle and allows
the deposition of cholesterol and the heart muscle. B6 may also be useful
in preventing oxalate kidney stones and acts as a mild diuretic. It
reduces the symptoms of premenstrual syndrome and is helpful in the
treatment of allergies, arthritis, and asthma. Carpal tunnel syndrome is
linked to a B6 deficiency.
Vitamin B12 (Cyanocobalamin): Vitamin B12 is needed to
prevent anemia. It aids in cell formation and cellular longevity. This
vitamin is also required for proper digestion, absorption of foods,
protein synthesis, and metabolism of carbohydrates and fats. In addition,
vitamin B12 prevents nerve damage, maintains fertility, and promotes
normal growth and development. A vitamin B12 deficiency can be caused by
malabsportion, which is most common in the elderly and in those with
digestive disorders. Vegetarians are also likely to have a B12 deficiency,
and must include foods with this vital nutrient. Deficiency symptoms
include abnormal gait, memory loss, hallucinations, eye disorders, anemia,
and digestive disorders.
Biotin: Biotin aids in cell growth, in fatty acid
production, in metabolism of carbohydrates, fats, and proteins, and in the
utilization of the B-complex vitamins. Sufficient quantities are needed
for healthy hair and skin. Biotin may prevent hair loss in some men.
Biotin also promotes healthy sweat glands, never tissue, and bone marrow.
A deficiency if this B vitamin is rare because it can be produced in the
intestines from foods.
Vitamin C (ascorbic acid): Vitamin C is an antioxidant
that is required for tissue growth and repair, adrenal gland function, and
healthy gums. It protects against the harmful effects of pollution,
prevents cancer, protects against infection, and enhances immunity. It
also may reduce cholesterol levels and high blood pressure, and prevent
arteriosclerosis. Essential in the formation of collagen, vitamin C
protects against blood clotting and bruising, and promotes the healing of
wounds and the production of anti-stress hormones. It also aids in
interferon production, and is needed for the metabolism of folic acid,
tyrosine, and phenylalanine. New evidence indicates that vitamin C and
vitamin E work better together than separately. Vitamin E scavenges for
dangerous oxygen radicals in the cell membrane, while vitamin C breaks
down the free radical chain in biological fluids. Both these vitamins have
greatly extended antioxidant activity.
Vitamin E (dl-alpha-tocopheryl acetate): Vitamin E is
an antioxidant that prevents cancer and cardiovascular disease. This
nutrient improves circulation, repairs tissue, and is useful in treating
fibrocystic breasts and premenstrual syndrome. It also promotes normal
clotting and healing, reduces scarring from some wounds, reduces blood
pressure, aids in preventing cataracts, improves athletic performance, and
aids leg cramps. Vitamin E also prevents cell damage by inhibiting lipid
peroxidation and the formation of free radicals. It retards aging and may
prevent age spots as well. The body needs zinc in order to maintain the
proper levels of vitamin E in the blood.
Folic Acid: Considered a brain food, folic acid is
needed for energy production and the formation of red blood cells.
Functioning as a coenzyme in DNA synthesis, it is important for healthy
cell division and replication. It is involved in protein metabolism and
has been used in the prevention and treatment of folic acid anemia. This
nutrient may also help depression and anxiety and may be effective in the
treatment of uterine cervical dysplasia. Folic acid helps regulate
embryonic and fetal development of nerve cells, vital for normal growth
and development. Folic acid works best when combined with vitamin B12. A
sore, red tongue is one sign of a deficiency. Attention: Oral
contraceptives may increase the need for folic acid.
Improving Mineral Absorption: Some mineral supplements
are available in chelated form, which means that the minerals are attached
to a protein molecule that transports them to the bloodstream in order to
enhance their absorption.
Calcium (stearate, caseinate and chelate): Calcium is
vital in the formation of strong bones and teeth and is also important in
the maintenance of regular heartbeat and the transmissions of nerve
impulses. It is needed for muscle growth and contraction and for the
prevention of muscle cramps. This important mineral is also essential in
blood clotting and helps prevent colon cancer. It may lower blood pressure
and prevent bone loss associated with osteoporosis as well. Calcium
provides energy and participates in the protein structuring of RNA and
DNA. It is also involved in the activation of several enzymes including
lipase. The amino acid lysine is needed for calcium absorption. Calcium
protects bones and teeth from lead by inhibiting absorption of this toxic
metal. If there is a calcium deficiency, lead will be absorbed by the body
and deposited in the teeth and bones. This may account for the higher
levels of lead in children who have a higher incidence of cavities. A
calcium deficiency may result in the following symptoms: muscle cramps,
nervousness, heart palpitations, brittle nails, eczema, hypertension,
aching joints, increased cholesterol levels, rheumatoid arthritis, tooth
decay, insomnia, rickets, and numbness in the arms and/or legs. Female
athletes and women experiencing menopause need greater amounts of calcium
due to lower estrogen levels. Estrogen protects the skeletal system by
promoting the deposits of calcium in bone.
Chromium (chelate): Because it is involved in the
metabolism of glucose, chromium (glucose tolerance factor or GTF) is
needed for energy. It is also vital in the synthesis of cholesterol, fats,
and protein. This essential mineral maintains stable blood sugar levels
through proper insulin utilization in both the diabetic and the
hypoglycemic. Low plasma chromium levels are an indication of coronary
artery disease. The average American diet is chromium deficient.
Researchers estimate that two out of every three Americans are either
hypoglycemic, pre-hypoglycemic, or diabetic. The ability to maintain
normal blood sugar levels is jeopardized by the lack of chromium in our
soil and water supply and by a diet in refined white sugar, flour, and
junk foods.
Copper (gluconate and chelate): Among its many
functions copper aids in the formation of bone, hemoglobin, and red blood
cells, and works in balance with zinc and vitamin C to form elastin. It is
involved in the healing process, energy production, hair and skin
coloring, and taste sensitivity. This mineral is also needed for healthy
nerves. One of the early signs of copper deficiency is osteoporosis.
Copper is essential for the formation of collagen, which makes up the
connective tissue of the bone matrix.
Iron (electrolytic and chelate): Perhaps the most
important of its functions is the production of hemoglobin and oxygenation
of the red blood cells. Iron is the mineral found in the largest amounts
in the blood. This mineral is essential for many enzymes, and is important
for growth in children and resistance to disease. Iron is also required
for a healthy immune system and for energy production. Vitamin C can
increase iron absorption as much as 30 percent. Iron deficiency symptoms
include brittle hair, nails that are spoon shaped or that have ridges
running lengthwise, hair loss, fatigue, dizziness, and anemia.
Magnesium (chelate): Magnesium is vital to enzyme
activity. It assists in calcium and potassium uptake. A deficiency
interferes with the transmission of nerve muscle impulses, causing
irritability and nervousness. Supplementing the diet with magnesium helps
prevent depression, dizziness, muscle weakness, twitching, heart disease,
and high blood pressure, and also aids in maintaining the proper pH
balance. This essential mineral protects the arterial lining from stress
caused by sudden blood pressure changes, and plays a role in the formation
of bone and in carbohydrate and mineral metabolism. With vitamin B6,
magnesium helps reduce and dissolve calcium phosphate stones.
Manganese (chelate): Minute quantities of manganese
are needed for protein and fat metabolism, healthy nerves, and healthy
immune system and blood sugar regulation. It is used for energy production
and is required for normal bone growth and reproduction. Manganese is
essential for iron-deficient anemics and is also needed for the
utilization of thiamine (B1) and vitamin E. Manganese works well with the
B-complex vitamins to give an overall feeling of well-being. It aids in
the formation of mother's milk and is a key element in the production of
enzymes needed to oxidize fats and to metabolize purines.
Potassium (iodide): This mineral is important for a
healthy nervous system and a regular rhythm. It helps prevent stroke, aids
in proper muscle contraction, and works with sodium to control the body's
water balance. Potassium is important for chemical reactions within the
cells and aids in maintaining stable blood pressure and in transmitting
electrochemical impulses. It also regulates the transfer of nutrients to
the cells.
Zinc (oxide and chelate): This essential mineral is
important in prostrate gland function and the growth of reproductive
organs. It is required for protein synthesis and collagen formation and
promotes a healthy immune system and the healing of wound. Zinc also
allows acuity of taste and smell and protects the liver from chemical
damage. Sufficient intake and absorption of zinc is needed to maintain the
proper concentrations of vitamin E in the blood.
Lactobacillus Acidophilus: These friendly bacteria
work by assisting in the digestion of proteins, a process in which lactic
acid, hydrogen peroxide, enzymes, antibiotic substances that inhibit
pathogenic organisms, and B vitamins are produced. Acidophilus helps to
detoxify harmful substances. Factors that contribute to candidiasis are
recurrent use of antibiotics, oral contraceptives, aspirin,
corticosteroids, prescription medications, poor diet, sugar, yeast, and
stress. These all cause an imbalance of the "friendly" bacteria. The good
flora bind with some of the unwanted substances, causing them to be
excreted. Antibiotics do not know the difference between good and bad
bacteria. When you flush antibiotics through your digestive system they
kill off your intestinal flora and cause immune system depression. That is
why it is better if you use natural methods for clearing infections and
bacterial problems. Consistent usage can cause health damages that will
plague you for years to follow! This is why you hear of yeast infections
and digestive problems when they are used. Your body is trying to tell you
something and you should be listening! Use Biomune OSF Plus if you have
repeated illness and need immune system help. There are no harmful side
effects and you can help your immune system instead of harming it!
Brain Teaser: After reading the above let's consider
the billions of dollars spent on cancer and other diseases that can be
attributed to lifestyle in general. "If you treat the disease, you
never win. You must treat the person with the disease, and then you will
succeed!"
In both Type 1 and Type 2 diabetes risk for heart
disease, hypertension, disorders of the nervous system, blindness and
kidney disease are elevated. In addition, diabetes can increase onešs risk
of complications to the fetus and/or mother during pregnancy. For this
reason diabetes can not simply be treated as a disorder in sugar
digestion. Rather, one must also consider all of the complications that
accompany the impaired glucose metabolism. The annual costs for prevention
and treatment of this serious condition exceeds $100 billion and this
amount continues to rise. Coronary heart disease (CHD) is the major cause
of death in most developed countries and is rapidly increasing in
prevalence in developing countries. In the US, for example, death rates
from cardiovascular disease exceed 1 million annually and the total cost
is estimated to exceed $120 billion, the largest disease-related cost to
health. While many modifiable risk factors, such as cigarette smoking and
hypertension, contribute to risk for CHD, lipid abnormalities are the most
important factors. Low-density lipoproteins (LDL) have a central role in
the atherosclerotic process. LDL penetrate the walls of blood vessels
where they are oxidized by free radicals and accumulate as a gruel-like
material that blocks the blood vessel lumen; this material also can leak
into the blood vessel to cause a thrombosis. High-density lipoproteins
(HDL) cholesterol have a protective effect and act to prevent LDL
oxidation and remove cholesterol that accumulates in the blood vessel
wall.
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